API5 Polyclonal Antibody Store at -20°C
SKU: E-AB-16168-200
API5 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16168 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human API5 |
| Abbre | API5 |
| Synonyms | AAC 11, AAC-11, AAC11, API 5, API-5, API5, API5 like 1, API5L1, Antiapoptosis clone 11 protein, Apoptosis inhibitor 5, Cell migration inducing gene 8 protein, Cell migration-inducing gene 8 protein, Fibroblast grow, Fibroblast growth factor 2 interacting factor 2, api5 |
| Swissprot | |
| Calculated MW | 59 kDa |
| Cellular Localization | Cytoplasm and Nucleus. Cytoplasm. Mainly nuclear. Can also be cytoplasmic. |
| Concentration | 1.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.