APC5 Polyclonal Antibody
SKU: E-AB-10810-200
APC5 Polyclonal Antibody
| SKU # | E-AB-10810 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ANAPC5 |
| Abbre | APC5 |
| Synonyms | 2510006G12Rik, AA408751, AA536819, AA986414, ANAPC 5, ANAPC5, APC5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, RMC1 |
| Swissprot | |
| Cellular Localization | Cytosol, Nucleus, anaphase-promoting complex, nucleoplasm, nucleus. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination.The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators.It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation.Multiple transcript variants encoding different isoforms have been found for this gene.