ANXA6 Polyclonal Antibody
SKU: E-AB-40260-200
ANXA6 Polyclonal Antibody
| SKU # | E-AB-40260 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Rat Annexin A6 protein |
| Abbre | ANXA6 |
| Synonyms | 67 kDa calelectrin, ANX 6, ANX A6, ANX6, ANXA 6, ANXA6, Annexin A6, Annexin VI, Annexin VI p68, Annexin-6, AnnexinA6, AnnexinVI, CBP 68, CBP68, Calcium binding protein p68, Calelectrin, Calphobindin II, Calphobindin-II, CalphobindinII, Chromobindin 20, Chromobindin-20 |
| Swissprot | |
| Calculated MW | 76 kDa |
| Observed MW | 72 kDa |
| Cellular Localization | Cytoplasm, Melanosome. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:4000 |
| IHC | 1:100-1:200 |
Background
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.