AMPD1 Polyclonal Antibody Store at -20°C
SKU: E-AB-16156-200
AMPD1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-16156 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human AMPD1 |
| Abbre | AMPD1 |
| Synonyms | AMP deaminase 1, AMP deaminase isoform M, AMPD, AMPD 1, Adenosine monophosphate deaminase 1, Adenosine monophosphate deaminase 1 (isoform M), Ampd01, MAD, MADA, Myoadenylate deaminase, RATAMPD01, Skeletal muscle AMPD |
| Swissprot | |
| Calculated MW | 90 kDa |
| Cellular Localization | Cytosol |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.