ALDH1A1/2/3 Polyclonal Antibody Store at -20°C
SKU: E-AB-13801-200
ALDH1A1/2/3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13801 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ALDH1A1/ALDH1A2/ALDH1A3 |
| Abbre | ALDH1A1/2/3 |
| Synonyms | ALDC, ALDH-E1, ALDH1, ALDH11, ALDH1A6, ALDH6, PUMB1, RALDH(II), RALDH1, RALDH2, RALDH2-T, RALDH3 |
| Swissprot | |
| Calculated MW | 57 kDa |
| Cellular Localization | Cytosol, Other locations: cytoplasm, perinuclear region of cytoplasm. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:150 |
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.