ADAM11 Polyclonal Antibody Store at -20°C
SKU: E-AB-12942-200
ADAM11 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12942 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ADAM11 |
| Abbre | ADAM11 |
| Synonyms | A disintegrin and metalloproteinase domain 11, ADA11, ADAM 11, Adam11, Disintegrin and metalloproteinase domain-containing protein 11, MDC, Metalloprote, Metalloproteinase like, and cysteine rich protein, and cysteine-rich protein, disintegrin like, disintegrin-like |
| Swissprot | |
| Calculated MW | 83 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.