14-3-3 theta Polyclonal Antibody
SKU: E-AB-12588-200
14-3-3 theta Polyclonal Antibody
| SKU # | E-AB-12588 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human YWHAQ |
| Abbre | YWHAQ |
| Synonyms | 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14 3 3 tau, 14 3 3 theta, 14-3-3 protein T-cell, 14-3-3 protein tau, 14-3-3 protein theta, 1433T, 1C5, HS1, KCIP1, Protein HS1, Protein kinase C inhibitor protein 1, Protein tau, tyr3/trp5 monooxygenase ac |
| Swissprot | |
| Calculated MW | 28 kDa |
| Cellular Localization | Cytoplasm. In neurons, axonally transported to the nerve terminals. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:25-1:100 |
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins.This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs.This gene is upregulated in patients with amyotrophic lateral sclerosis.It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.