WTAP Polyclonal Antibody Reactivity Human
SKU: E-AB-52415-200
WTAP Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52415 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | WTAP |
| Synonyms | DKFZp686F20131, FL2D, Female-lethal(2)D homolog, KIAA0105, MGC3925, Mum2, OTTHUMP00000017522, OTTHUMP00000017523, PNAS 132, PNAS-132, PNAS132, Pre mRNA splicing regulator WTAP, Pre-mRNA-splicing regulator WTAP, Putative pre mRNA splicing regulator female letha, hFL(2)D |
| Swissprot | |
| Cellular Localization | Nucleus>nucleolus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
WTAP,also named as KIAA0105 and hFL(2)D,is previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. It is a Pre-mRNA-splicing regulator protein. It is a regulatory subunit of the WMM N6-methyltransferase complex which plays a role in the efficiency of mRNA splicing and processing and mRNA stability. It is required for accumulation of METTL3 and METTL14 to nuclear speckle.