TNFRSF21 Polyclonal Antibody
SKU: E-AB-12371-200
TNFRSF21 Polyclonal Antibody
| SKU # | E-AB-12371 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TNFRSF21 |
| Abbre | TNFRSF21 |
| Synonyms | BM 018, BM018, CD358, DR 6, DR6, Death receptor 6, MGC31965, OTTHUMP00000039915, TNFR related death receptor 6, TNFRSF 21, TNFRSF21, TNFRSF21 protein, TNR21, Tumor necrosis factor receptor superfamily member 21, Tumor necrosis factor receptor superfamily member 21 prec |
| Swissprot | |
| Calculated MW | 72 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.