TNF Beta Polyclonal Antibody Store at -20°C
SKU: E-AB-14410-200
TNF Beta Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14410 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human LTA |
| Abbre | LTA |
| Synonyms | DIF, LT, LT alpha, LT-alpha, LTalpha, Lta, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, Lymphotoxin-alpha, TNF, TNF B, TNF superfamily member 1, TNF-beta, TNFB, TNFSF1, TNFbeta, TNLG1E, Tumor necrosis factor beta, lymphocyte-derived, member 1), tumor necrosis |
| Swissprot | |
| Cellular Localization | Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.