TGF β Receptor I Polyclonal Antibody Store at -20°C
SKU: E-AB-12904-200
TGF β Receptor I Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12904 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TGFBR1 |
| Abbre | TGFBR1 |
| Synonyms | 53kD, 53kDa, AAT 5, AAT5, Activin A receptor type II like kinase, Activin A receptor type II like kinase 53kDa, Activin A receptor type II like protein kinase of 53kD, activin A receptor type II-like kinase, activin A receptor type II-like protein kinase of 53kD |
| Swissprot | |
| Cellular Localization | Cytoplasm |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.