TERF2 Polyclonal Antibody Store at -20°C
SKU: E-AB-15871-200
TERF2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15871 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TERF2 |
| Abbre | TERF2 |
| Synonyms | TERF 2, TERF2, TRBF 2, TRBF2, TRF 2, TRF2, TTAGGG repeat binding factor 2, TTAGGG repeat-bind, Telomeric DNA binding protein, Telomeric DNA-binding protein, Telomeric repeat binding factor 2, Telomeric repeat binding protein 2, Telomeric repeat-binding factor 2, Terf2 |
| Swissprot | |
| Cellular Localization | Nucleus. Chromosome>telomere. Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.