SPTAN1 Polyclonal Antibody Host Rabbit
SKU: E-AB-40268-200
SPTAN1 Polyclonal Antibody Host Rabbit
| SKU # | E-AB-40268 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Rat Spectrin alpha chain, non-erythrocytic 1 protein |
| Abbre | SPTAN1 |
| Synonyms | (ALPHA)II-SPECTRIN, Alpha II Spectrin, Alpha-II spectrin, EIEE5, FLJ17738, FLJ44613, Fodrin, Fodrin alpha chain, NEAS, Non erythrocytic spectrin alpha, SPECA, Spectrin alpha chain, Spectrin alpha chain brain, Spectrin alpha non er, alpha, brain, non-erythroid alpha chain |
| Swissprot | |
| Calculated MW | 285,282 kDa |
| Observed MW | 280 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton. Cytoplasm>cell cortex. Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Signal Transduction, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:2000 |
| IHC | 1:100-1:400 |
Background
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation.