SCN5A Polyclonal Antibody
SKU: E-AB-12860-200
SCN5A Polyclonal Antibody
| SKU # | E-AB-12860 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SCN5A |
| Abbre | SCN5A |
| Synonyms | CDCD2, CMD1E, CMPD2, Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, PFHB1, SCN5A, Scn5a, Scn5a (gene name), Sodium channel protein cardiac muscle , Sodium channel protein cardiac muscle alpha subunit |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.