Recombinant Human BCAN Protein (His Tag)
SKU: PKSH032130-50
Recombinant Human BCAN Protein (His Tag)
| SKU # | PKSH032130 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | BCAN, BEHAB, Brain-Enriched Hyaluronan-Binding Protein, Brevican Core Protein, CSPG7, Chondroitin Sulfate Proteoglycan 7 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Asp23-Pro911 |
| Accession | AAH09117.1 |
| Calculated Molecular Weight | 97.8 kDa |
| Observed Molecular Weight | 75-150 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Brevican Core Protein (BCAN) is a secreted protein that belongs to the aggrecan/versican proteoglycan family. BCAN contains one C-type lectin domain, one EGF-like domain, one Ig-like V-type domain, one Sushi (CCP/SCR) domain and two Link domains. BCAN may play a role in the terminally differentiating and the adult nervous system during postnatal development. BCAN could stabilize interactions between hyaluronan (HA) and brain proteoglycans.