RASSF7 Polyclonal Antibody
SKU: E-AB-11525-200
RASSF7 Polyclonal Antibody
| SKU # | E-AB-11525 |
| Reactivity | Human, |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human RASSF7 |
| Abbre | RASSF7 |
| Synonyms | C11orf13, Chromosome 11 open reading frame 13, HRAS1, HRAS1 related cluster 1, HRAS1 related cluster protein 1, HRAS1-related cluster protein 1, HRC1, MGC126069, MGC126070, Ras association (RalGDS/A, Ras association (RalGDS/AF 6) domain family (N terminal) member 7 |
| Swissprot | |
| Calculated MW | 40 kDa |
| Cellular Localization | Cytoskeleton, microtubule organizing center, Other locations: cytoplasm. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome.RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family.Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis.Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.