PYGL Polyclonal Antibody Store at -20°C
SKU: E-AB-11510-200
PYGL Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11510 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PYGL |
| Abbre | PYGL |
| Synonyms | GSD6, Glycogen phosphorylase, Glycogen phosphorylase L, Glycogen phosphorylase liver, Glycogen phosphorylase liver form, Hers disease, OTTHUMP00000233649, OTTHUMP00000233651, PYGL, Phosphorylase glycogen liver, Pygl, glycogen storage disease type VI, liver form |
| Swissprot | |
| Calculated MW | 97 kDa |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, extracellular region, Other locations: cytoplasm, ficolin-1-rich granule lumen, secretory granule lumen. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:30-1:150 |
Background
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores.This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15.Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls.Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.