PRDX1 Monoclonal Antibody
SKU: E-AB-22067-200
PRDX1 Monoclonal Antibody
| SKU # | E-AB-22067 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Applications | WB, IHC-p, IF |
Product Details
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p, IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein |
| Abbre | Peroxiredoxin 1 |
| Synonyms | Heme binding 23 kDa protein, MSP23, NKEF A, NKEF-A, NKEFA, Natural killer cell-enhancing factor A, OSF3, Osteoblast specific factor 3, PAG, PAGB, PRDX1, PRX1, Paga, Peroxiredoxin-1, Proliferation associated gene A, Proliferation-associated gene protein, PrxI, TDPX2 |
| Swissprot | |
| Observed MW | 21 kDa |
| Cellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism |
| Clone No. | 2J5 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:3000 |
| IHC | 1:50-1:300 |
| IF | 1:100-1:200 |
Background
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.