PPM1B Polyclonal Antibody Reactivity Human
SKU: E-AB-52842-200
PPM1B Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52842 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PPM1B |
| Abbre | PPM1B |
| Synonyms | MGC21657, OTTHUMP00000158953, OTTHUMP00000158954, OTTHUMP00000158955, OTTHUMP00000202394, OTTHUMP00000202395, OTTHUMP00000202399, PP2C beta, PP2C beta X, PP2C-beta, PP2CB, PP2Cbeta, PPC2BETAX, PPM 1B, PPM1B, Ppm1b, Protein phosphatase 1B (formerly 2C) magnesium dependent |
| Swissprot | |
| Concentration | 1.44 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.