PABPC1 Polyclonal Antibody Store at -20°C
SKU: E-AB-11389-200
PABPC1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11389 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PABPC1 |
| Abbre | PABPC1 |
| Synonyms | PAB 1, PAB1, PABP 1, PABP1, PABPC 1, PABPC1, PABPC2, PABPL1, Poly A binding protein 1, Poly A binding protein cytoplasmic 1, Polyadenylate binding protein 1, cytoplasmic 1, cytoplasmic 2, poly(A) binding protein |
| Swissprot | |
| Calculated MW | 71 kDa |
| Cellular Localization | Cytoplasmic. Shuttles between the cytoplasm and the nucleus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
Background
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.