NOL3 Polyclonal Antibody Store at -20°C
SKU: E-AB-14591-200
NOL3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14591 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NOL3 |
| Abbre | NOL3 |
| Synonyms | ARC, Apoptosis repressor with CARD, MYC, MYP, Muscle enriched cytoplasmic protein, Muscle-enriched cytoplasmic protein, NOL3, NOP, Nol3, Nop30, Nucleolar protein 3, Nucleolar protein 3 (apoptosis repressor with CARD domain), Nucleolar protein of 30 kDa |
| Swissprot | |
| Cellular Localization | Cytoplasm and Nucleus>nucleolus. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.