NAE1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14592-200
NAE1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14592 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NAE1 |
| Abbre | NAE1 |
| Synonyms | 59 kDa, A 116A10.1, Amyloid beta precursor , Amyloid beta precursor protein binding protein 1, Amyloid beta precursor protein binding protein 1 59kD, Amyloid beta precursor protein binding protein 1 59kDa |
| Swissprot | |
| Calculated MW | 60 kDa |
| Cellular Localization | Cell membrane. Colocalizes with APP in lipid rafts. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
Background
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.