MST1/MST1/MST1/MST1/STK4 Polyclonal Antibody
SKU: E-AB-93353-200
MST1/MST1/MST1/MST1/STK4 Polyclonal Antibody
| SKU # | E-AB-93353 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC, IF |
Product Details
| sotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human MST1/MST1/MST1/MST1/STK4 |
| Abbre | MST1/MST1/MST1/MST1/STK4 |
| Synonyms | KRS2, MST1, YSK3, serine/threonine kinase 4, STK4 |
| Swissprot | |
| Calculated MW | 52 kDa/55 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm, Nucleus. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:100 |
| IF | 1:50-1:200 |
Background
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.