Thank you!

Your quote has been successfully submitted!

For products requiring additional information, our team will contact you within 1 business day

Failed

There was an error submitting your quote. Please try again.

MSE PRO tBuBrettphos, 98% Purity– MSE Supplies LLC

Free Shipping on MSE PRO Online Orders of $500 or More! U.S. Orders Only * Offer Excludes Hazmat Shipments *

Menu

This product has been added to the cart.

MSE PRO Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos), 98% Purity

SKU: CM1317

  • $ 29995


MSE PRO™ Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos), 98% Purity

MSE PRO™ Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos) is a highly efficient dialkylbiaryl phosphine ligand developed by the Buchwald group. It is renowned for its significant enhancement of cross-coupling reactions and reactivity in comparison to alternative catalytic systems. Notable examples of its effectiveness include its application in Pd-catalyzed conversion reactions of aryl and vinyl triflates, O-arylation of ethyl acetohydroximates, and conversion of aryl chlorides, triflates, and nonaflates to nitroaromatics.

MSE Supplies offers various catalysts and ligands of coupling reaction. Please contact us for customization or bulk orders.

Technical Specifications:

CAS No. 1160861-53-9
EINECS No. 811-756-3
Chemical name Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine
Synonym(s)
  • tBuBrettPhos
  • Di(tert-butyl)(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine

Molecular formula C31H49O2P
Pack size

1 g (CM1317)

5 g (CM1318)

Molecular weight 484.7 g/mol
Purity 98 %
Melting point 166-170 °C
Appearance White solid
Storage  Keep in Inert atmosphere, store at 2-8°C.


References:

[1] Gioria, E., Del Pozo, J., Martínez‐Ilarduya, J. M., & Espinet, P. (2016). Promoting difficult carbon–carbon couplings: which ligand does best?. Angewandte Chemie128(42), 13470-13474.

[2] Seo, T., Kubota, K., & Ito, H. (2020). Selective mechanochemical monoarylation of unbiased dibromoarenes by in situ crystallization. Journal of the American Chemical Society142(22), 9884-9889.