MSE PRO 2-Azabicyclo[2.2.1]hept-5-en-3-one, ≥98.0% Purity

$ 169⁹⁵

MSE PRO™ 2-Azabicyclo[2.2.1]hept-5-en-3-one, ≥98.0% Purity

MSE PRO™ 2-Azabicyclo[2.2.1]hept-5-en-3-one is a unique bicyclic heterocyclic compound containing a strained ring system and a reactive ketone functionality, making it an excellent synthon for complex molecule synthesis. It is widely used as a key intermediate in the production of various drugs and pharmaceutically active compounds due to its structural features and reactivity. Additionally, it serves as a crucial precursor in the synthesis of carbocyclic nucleosides, which have shown promising biological activities and therapeutic potential.

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Technical Specifications:

CAS No.	49805-30-3
Chemical name	2-Azabicyclo[2.2.1]hept-5-en-3-one
Synonym(s)	4-Amino-2-cyclopentene-1-carboxylic acid lactam 3-Azabicyclo[2.2.1]hepta-5-ene-2-one
Molecular formula	C₆H₇NO
Pack size	100 g (CM1360); 500 g (CM1361)
Molecular weight	109.13 g/mol
Boiling point	102-106 °C (lit.)
Melting point	54-58 °C (lit.)
Density	1.1143 (Estimate)
Purity	98.34% (LCMS)
pKa	15.48±0.20 (Predicted)
Appearance	Off-white to light brown solid
Storage	Store at room temperature

Note: lit. means the data is stated according to related literature.

References:

[1] Singh, R., & Vince, R. (2012). 2-Azabicyclo [2.2. 1] hept-5-en-3-one: chemical profile of a versatile synthetic building block and its impact on the development of therapeutics. Chemical Reviews, 112(8), 4642-4686.

[2] Aljarilla, A., & Plumet, J. (2008). Tuning the Chemoselectivity of the Metathesis Reactions of N‐Substituted 2‐Azabicyclo [2.2. 1] hept‐5‐en‐3‐one.