MORC2 Polyclonal Antibody Reactivity Human
SKU: E-AB-52244-200
MORC2 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52244 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MORC2 |
| Abbre | MORC2 |
| Synonyms | AC004542.C22.1., CW type with coiled coil domain 1, KIAA0852, MORC family CW type zinc finger 2, MORC family CW-type zinc finger protein 2, MORC2, ZCW3, ZCWCC1, Zinc finger, Zinc finger CW type coiled coil domain protein 1, Zinc finger CW type with coiled coi |
| Swissprot | |
| Calculated MW | 118 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Cytoplasm, cytosol. Mainly located in the nucleus. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The CW domain is a structural module found in many vertebrate, parasitic and plant proteins. It consists of a mononuclear four-cysteine zinc-finger domain that plays a role in DNA binding, chromatin methylation and early embryonic development. ZCWCC1 (zinc finger CW-type coiled-coil domain protein 1), also known as MORC2 (MORC family CW-type zinc finger protein 2) or ZCW3, is a 1,032 amino acid protein that contains one CW-type zinc finger domain. ZCWCC1 is located on chromosome 22 and is ubiquitously expressed with highest expression in pancreas, smooth muscle and testis. Expression of ZCWCC1 is upregulated in hypoxia, a pathological condition characterized by an inadequate supply of oxygen in the blood.