LRP5 Polyclonal Antibody Store at -20°C
SKU: E-AB-12546-200
LRP5 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12546 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human LRP5 |
| Abbre | LRP5 |
| Synonyms | BMND1, EVR1, EVR4, HBM, LR3, LRP-5, LRP5, LRP7, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, Lrp5, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma syndrome, VBCH2 |
| Swissprot | |
| Cellular Localization | Membrane. Endoplasmic reticulum. Chaperoned to the plasma membrane by MESD. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.