LRIG3 Polyclonal Antibody
SKU: E-AB-12545-200
LRIG3 Polyclonal Antibody
| SKU # | E-AB-12545 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human LRIG3 |
| Abbre | LRIG3 |
| Synonyms | LIG-3, LIG3, LRIG1-3, LRIG3, Leucine-rich repeats and immunoglobulin-like domains protein 3, Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3, Lrig3 |
| Swissprot | |
| Cellular Localization | Cell membrane. Cytoplasmic vesicle membrane. Detected in cytoplasmic vesicles when coexpressed with ERBB4. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Developmental Biology, Neuroscience, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:25-1:100 |
Background
Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis.Lrig3 was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages.A prominent consequence of the morpholino-induced inhibition of Lrig3 expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3.