ITPKC Polyclonal Antibody Reactivity Human
SKU: E-AB-52036-200
ITPKC Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52036 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ITPKC |
| Abbre | ITPKC |
| Synonyms | 4, 5 trisphosphate 3 kinase C, 5-trisphosphate 3-kinase C, IP3 3-kinase C, IP3 3KC, IP3K C, IP3KC, Inositol 1, Inositol trisphosphate 3 kinase C, Inositol-trisphosphate 3-kinase C, InsP 3 kinase C, InsP 3-kinase C, Itpkc, inositol 1 |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm. Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.ITPKC (Inositol-Trisphosphate 3-Kinase C) is a Protein Coding gene. Diseases associated with ITPKC include Kawasaki Disease and Lymph Node Disease. Among its related pathways are Inositol phosphate metabolism (KEGG) and Calcium signaling pathway. GO annotations related to this gene include calmodulin binding and inositol-1,4,5-trisphosphate 3-kinase activity. An important paralog of this gene is ITPKB.