HSP40 Polyclonal Antibody Store at -20°C
SKU: E-AB-14642-200
HSP40 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14642 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human DNAJB1 |
| Abbre | HSP40 |
| Synonyms | DNAJ 1, DNAJ B1, DNAJ1, DNAJB 1, DNAJB1 protein, DNJB1, DnaJ (Hsp40) homolog subfmaily B member 1, DnaJ heat shock protein family (Hsp40) member B1, DnaJ homolog subfamily B member 1, DnaJ protein homolog 1, Dnajb1, HDJ 1, HDJ-1, HDJ1, Heat , Heat shock 40 kDa protein 1 |
| Swissprot | |
| Calculated MW | 38 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Nucleus>nucleolus. Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association between HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. There are five known HSP 40 family proteins.