HK1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14707-200
HK1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14707 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HK1 |
| Abbre | HK1 |
| Synonyms | BB404130, Brain form hexokinase, DrHXK1, EC 2.7.1.1, Glycolytic enzyme, HEXOKIN, HK I, HK1, HK1 tb, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, Hexokinase, Hexokinase PI, Hexokinase type I, Hexokinase-1, Hexokinase-A, Hk1-s, dea, hexokinase I, im:7148527, mH, tumor isozyme |
| Swissprot | |
| Cellular Localization | Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms.