HCK Polyclonal Antibody Store at -20°C
SKU: E-AB-14119-200
HCK Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14119 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human HCK |
| Abbre | HCK |
| Synonyms | Bmk, HCK, Hck, Hck 1, Hemopoietic cell kinase, JTK9, Tyrosine protein kinase HCK, Tyrosine-protein kinase HCK, p59-HCK/p60-HCK, p59HCK/p60HCK, p59Hck, p61Hck |
| Swissprot | |
| Calculated MW | 60 kDa |
| Cellular Localization | Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane>caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases.This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages.It may help couple the Fc receptor to the activation of the respiratory burst.In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils.Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.