GSTA3 Polyclonal Antibody Store at -20°C
SKU: E-AB-11286-200
GSTA3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11286 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human GSTA3 |
| Abbre | GSTA3 |
| Synonyms | Glutathione S alkyltransferase A3, Glutathione S aralkyltransferase A3, Glutathione S aryltransferase A3, Glutathione S transfe, Glutathione S transferase A3, Glutathione S transferase A3 3, Glutathione S transferase alpha 3, glutathione S transferase A3 subunit |
| Swissprot | |
| Calculated MW | 25 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6.Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity.However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.