FTO Polyclonal Antibody Store at -20°C
SKU: E-AB-11248-200
FTO Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11248 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human FTO |
| Abbre | FTO |
| Synonyms | ALKBH9, AW743446, AlkB homolog 9, Alpha-ketoglutarate-dependent dioxygenase FTO, FATSO, FTO, Fat mass and obesity-associated protein, Fto, GDFD, HOMOLOG OF, KIAA1752, MOUSE, Protein fatso, mKIAA1752 |
| Swissprot | |
| Calculated MW | 58 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.