EMC8 Polyclonal Antibody Store at -20°C
SKU: E-AB-14013-200
EMC8 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14013 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human EMC8 |
| Abbre | EMC8 |
| Synonyms | C16orf2, C16orf4, COX4, COX4 neighbor, COX4AL, CX4NB, Cox4nb, ER membrane protein complex subunit 8, FAM158B, NOC4, Neighbor of COX4, Protein FAM158B, family with sequence similarity 158, member B, neighbor of |
| Swissprot | |
| Calculated MW | 24 kDa |
| Cellular Localization | Cytosol, Endoplasmic reticulum, ER membrane protein complex, Mitochondrion, Nucleus, Other locations: cytoplasm, membrane. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.