DRAK2 Polyclonal Antibody Store at -20°C
SKU: E-AB-14744-200
DRAK2 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14744 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human STK17B |
| Abbre | DRAK2 |
| Synonyms | DAP kinase related apoptosis inducing protein, DAP kinase related apoptosis inducing protein kinase 2, DAP kinase-related apoptosis-inducing protein kinase 2, DRAK 2, DRAK2, Death associated protein kinase related 2, Serine/threonine, Serine/threonine kinase 17b |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD.The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases.STK17A and STK17B share 59.7% amino acid identity.Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region.Transient transfection of COS-7 cells showed that STK17B localized in nuclei.Phosphorylates myosin light chains.Acts as a positive regulator of apoptosis.