CYP11A1 Polyclonal Antibody Store at -20°C
SKU: E-AB-14914-200
CYP11A1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14914 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CYP11A1 |
| Abbre | CYP11A1 |
| Synonyms | CP11A, CYP11A, CYP11A1, CYPXI, Cholesterol 20 22 desmolase, Cholesterol desmolase, Cholesterol monooxygenase (side chain cleaving), Cholesterol side chain cleavage enzyme, Cholesterol side chain cleavage enzyme mitochondrial, Cholesterol side-chain cleavage enzyme |
| Swissprot | |
| Cellular Localization | Mitochondrion membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.