CMPK1 Polyclonal Antibody
SKU: E-AB-52550-200
CMPK1 Polyclonal Antibody
| SKU # | E-AB-52550 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | CMPK1 |
| Synonyms | CMK, CMPK, CMPK 1, Cytidine monophosphate (UMP CMP) kinase 1 cytosolic, Cytidine monophosphate UMP CMP kinase 1 cytosolic, Cytidine monophosphate kinase, Cytidylate kinase, Deoxycytidylate kinase, EC 2.7.4.14, KCY, Monophosphatase kinase, OTTHU, cmpk1, dCMP kinase |
| Swissprot | |
| Calculated MW | 22 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Cytoplasm. Mainly nuclear. |
| Concentration | 0.66 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.