ASCL1 Polyclonal Antibody Store at -20°C
SKU: E-AB-15516-200
ASCL1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15516 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ASCL1 |
| Abbre | ASCL1 |
| Synonyms | Achaete scute complex homolog 1, Achaete scute complex homolog like 1, Achaete scute complex homologue 1, Achaete scute complex homologue like 1, Achaete scute complex like 1, Achaete scute family bHLH transcription factor 1, Achaete scute protein, Achaete-scute |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.