ARF6 Polyclonal Antibody Store at -20°C
SKU: E-AB-12250-200
ARF6 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12250 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ARF6 |
| Abbre | ARF6 |
| Synonyms | ADP ribosylation factor 6, ADP ribosylation factor protein 6, ADP-ribosylation factor 6, ARF6, DKFZp564M0264, Small GTP binding protein, Small GTPase |
| Swissprot | |
| Calculated MW | 20 kDa |
| Cellular Localization | Golgi apparatus. Cell membrane. Endosome membrane. Cell membrane. Cell projection>filopodium membrane. Recruited to the cell membrane in association with CYTH2 and ARL4C. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.