AMBRA1 Polyclonal Antibody
SKU: E-AB-10787-200
AMBRA1 Polyclonal Antibody
| SKU # | E-AB-10787 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human AMBRA1 |
| Abbre | AMBRA1 |
| Synonyms | AMRA1, Activating molecule in BECN1 regulated autophagy protein 1, Activating molecule in BECN1-regulated autophagy protein 1, Activating molecule in beclin 1 regulated autophagy, Ambra1, Autophagy and beclin 1 regulator 1, DCAF3, FLJ20294, Hypothetical protein F |
| Swissprot | |
| Cellular Localization | Cytoplasmic vesicle>autophagosome. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.