ALDH5A1 Polyclonal Antibody Store at -20°C
SKU: E-AB-12961-200
ALDH5A1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12961 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ALDH5A1 |
| Abbre | ALDH5A1 |
| Synonyms | ALDH5A 1, Aldedehyde dehydrogenase 5 family, Aldehyde dehydrogenase 5 family member A1, Aldehyde dehydrogenase 5A1, Aldehyde dehydrogenase family 5 member A1, Aldh5a1, Mitochondrial succinate semialdehyde dehydrogenase, NAD(+) dependent succinic se, mitochondrial |
| Swissprot | |
| Cellular Localization | Mitochondrion. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.