ACVR2A Polyclonal Antibody Reactivity Human
SKU: E-AB-12278-200
ACVR2A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-12278 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ACVR2A |
| Abbre | ACVR2A |
| Synonyms | ACTR 2, ACTR IIA, ACTR-IIA, ACTR2, ACTRII, ACTRIIA, ACVR2A, AVR2A, Activin A receptor type IIA, Activin receptor type 2A, Activin receptor type IIA, Activin receptor type-2A, Acvr 2, Acvr 2A, Acvr2, OTTHUMP00000197918 |
| Swissprot | |
| Calculated MW | 58 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain.