ACTL6B Polyclonal Antibody Reactivity Human
SKU: E-AB-52947-200
ACTL6B Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52947 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ACTL6B |
| Abbre | ACTL6B |
| Synonyms | 53 kDa BRG1 associated factor B, 53 kDa BRG1-associated factor B, ACL 6B, ACL6B, Actin like 6, Actin like protein 6B, Actin like protein6B, Actin related protein, Actin related protein Baf53b, Actin-like protein 6B, Actin-related protein Baf53b, actin-like 6B |
| Swissprot | |
| Calculated MW | 47 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Stem cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins.Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling.This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S.cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression.This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.Alternative splicing results in multiple transcript variants.