MSE PRO™ Hollow Mesoporous Manganese Dioxide Nanoparticles Water Solution, 1 mg/mL

Nanostructured MnO₂ can decompose H⁺ or GSH in TME and enhance T1-MR imaging contrast. They can also increase oxygen levels, aiding in cancer therapies. They have been demonstrated to be excellent drug loading/delivery systems to load high quantities of therapeutic agents, whose release may be precisely controlled by tuning the shell structures or coatings.

MSE Supplies offers a variety of nanoparticles and other high purity inorganic chemicals. Please contact us for more information.

Specifications:

Product name	Hollowmesoporous manganese dioxide nanoparticles
SKU#	PO9616, PO9618	PO9617, PO9619
Diameter	100-130 nm (TEM)	140-180 nm (TEM)
Zeta potential	-26 mV	-35 mV
Concentration	1 mg/mL
Main ingredient	MnO₂
Appearance	Grey black dispersion
Solvent	Water
Storage	Keep at 4°C, away from light, and sealed.

Note: This zeta potential is a single measurement data, data may vary between different batches.

Reference:

[1] Yang, G., Xu, L., Chao, Y. et al. Hollow MnO₂ as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses. Nat Commun 8, 902 (2017). https://doi.org/10.1038/s41467-017-01050-0.

[2] Xu, W., Qing, X., Liu, S., Yang, D., Dong, X., & Zhang, Y. (2022). Hollow mesoporous manganese oxides: Application in cancer diagnosis and therapy. Small, 18(15), 2106511.

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