SOD2 Polyclonal Antibody
SKU: E-AB-93344-200
SOD2 Polyclonal Antibody
| SKU # | E-AB-93344 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC, IF |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human SOD2 |
| Abbre | SOD2 |
| Synonyms | IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD, superoxide dismutase 2, SOD2 |
| Swissprot | |
| Calculated MW | 18 kDa/19 kDa/20 kDa/24 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Mitochondrion matrix. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
| IF | 1:50-1:200 |
Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.