SLC22A6 Polyclonal Antibody
SKU: E-AB-12825-200
SLC22A6 Polyclonal Antibody
| SKU # | E-AB-12825 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SLC22A6 |
| Abbre | SLC22A6 |
| Synonyms | FLJ55736, MGC45260, OAT1, OTTHUMP00000236796, OTTHUMP00000236797, OTTHUMP00000236798, OTTHUMP00000236799, Organic anion transporter 1, PAH transporter, PAHT, Para aminohippurate transporter, ROAT1, Renal organic anion transporter 1, S22A6, SLC22A6, So, hOAT1, hPAHT, hROAT1 |
| Swissprot | |
| Calculated MW | 56 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.