PTH1R Polyclonal Antibody Reactivity Human
SKU: E-AB-52894-200
PTH1R Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52894 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PTH1R |
| Abbre | PTH1R |
| Synonyms | MGC138426, MGC138452, PTH recep, Parathyroid hormone 1 receptor, Parathyroid hormone/parathyroid hormone related peptide receptor, Parathyroid hormone/parathyroid hormone related protein receptor, Parathyroid hormone/parathyroid hormone-related peptide receptor |
| Swissprot | |
| Cellular Localization | Cell membrane. |
| Concentration | 0.96 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]