PRPF3 Polyclonal Antibody Reactivity Human
SKU: E-AB-52769-200
PRPF3 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52769 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PRPF3 |
| Abbre | PRPF3 |
| Synonyms | S. crevisiae, homolog of, HPRP3P, PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae), PRPF3, Pre mRNA splicing factor 3, Pre-mRNA-splicing factor 3, Precursor mRNA-processing factor 3, Prp3p, RP18, SNRNP90, U4/U6 small nuclear ribonucleoprotein , hPrp3 |
| Swissprot | |
| Calculated MW | 78 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus speckle. Colocalizes with spliceosomal snRNPs. |
| Concentration | 0.54 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:20-1:100 |
Background
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18.