PPM1G Polyclonal Antibody Reactivity Human
SKU: E-AB-52759-200
PPM1G Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52759 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PPM1G |
| Abbre | PPM1G |
| Synonyms | MGC1675, MGC2870, OTTHUMP00000123426, PP2C, PP2C gamma, PP2C-gamma, PP2CG, PP2Cgamma, PPM1G, PPM1G_HUMAN, PPP2CG, Protein phospha, Protein phosphatase 1C, Protein phosphatase 1G, Protein phosphatase 2 catalytic subunit gamma isoform, Protein phosphatase 2C gamma isoform |
| Swissprot | |
| Cellular Localization | Cytoplasm, Membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology, Signal Transduction, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.